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KMID : 0371219920140010121
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Medical Bulletin of the Presbyterian Medical Center
1992 Volume.14 No. 1 p.121 ~ p.128
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Recent Trend of Multimodality Treatment of the Malignant Anal Tumor
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Abstract
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The malignant anal tumor is relatively rare, and abdominoperineal resection was mainstream of the treatment in the past, But, in recent, multimodality treatment of radiotherapy and systemiic chemotherapy was tried, and good results were reported
in
many
papers.
So, we reviewed the 71 cases of the primary malignant anal tumors which were treated at the department of general surgery, Presbyterian Medical Center, chonju, from Jan. 1963 to Dec. 1990.
@ES The results were as follows:
@EN 1) The incidence of the malignant anal tumor was 0.3% of total malignant tumors and 6% of coloanorectal cancer.
2) The ratio of male to female was 7.9:1, and peak age was 50th years old(N:24, range: 31-78 years old)
3) The symptom and signs were bleeding pain, constipation, mass, tenesmus, etc, in order.
4) 41 patients(58% of all) had the past history of hemorrhoid, abscess, prolapse, fissure, fistula, rectal rosing agent injection therapy.
5) The primary site of the malignant anal tumors were histlogical and margin; 36 cases(51%), histological anal canal. 22 cases(31%), and undefined; 13 cases, and pathologic diagnoses of the cloacogenic carcinoma; 2 cases, mixed carcinoma; 1
case,
and
malignant melanoma; 1 case.
6) The clinical stages(by AJCC, 1989) were classified as stage I;2 cases, stage II; 14 cases, stage III; cases(biopsy; 28 cases, palliative colostomy; 7 cases, palliative radiotherapy; 3 cases, electrofulguration; 2 cases) and curative
treatment;
31
cases(abdominoperineal resection; 7cases, APR with radiotherapy; 11 cases, curative radiotherapy; 5 cases, and chemoradiotherapy; 8 cases).
7) The overall five yerar survival rate according to treatment was 0% in palliative treatment and 53% in curative treatment, and the five year survival rate according to curative treatment modality was 100% in chemoradiotherapy 55% in APR with
radiotherapy, 43% in APR only, 40% in curative radiotherapy
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KEYWORD
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